Clinical Literature Library

Bronchial Valve Treatment: Past, Present and Future. Proceedings of Olympus Meeting at ATS 2012.

Complete unilateral versus partial bilateral endoscopic lung volume reduction in patients with bilateral lung emphysema

Eberhardt R, Gompelmann D, Schuhmann M, et al. Complete unilateral versus partial bilateral endoscopic lung volume reduction in patients with bilateral lung emphysema. Chest 2012; 142(4):900-908; doi: 10.1378/chest.11-2886

This study was conducted using complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity proven by native thin-slice CT (HRCT) scan and confirmed by perfusion scintigraphy.

A Randomized Study of Endobronchial Valves for Advanced Emphysema

Scuirba F, Ernst A, Herth FJF, et al. A Randomized Study of Endobronchial Valves for Advanced Emphysema. NEJM 2010; 363:1233-1244

This study involved the Zephyr^® Endobronchial Valve. Zephyr is a registered trademark of PulmonX, Inc.

Diagnostic Performance Comparison of the Chartis System and High-Resolution Computerized Tomography Fissure Analysis for Planning Endoscopic Lung Volume Reduction

Fully automatic quantitative assessment of emphysema in computed tomography: comparison with pulmonary function testing and normal values

Heussel CP, Herth FJF, Kappes J, et al. Fully automatic quantitative assessment of emphysema in computed tomography: comparison with pulmonary function testing and normal values. Eur Radiol 2009; 19: 2391–2402; doi 10.1007/s00330-009-1437-z Studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.