Clinical Literature Library

Incomplete fissures in severe emphysematous patients evaluated with MDCT: Incidence and interobserver agreement among radiologists and pneumologists

Koenigkam-Santos M, Puderbach M, Gompelmann D, et al. Incomplete fissures in severe emphysematous patients evaluated with MDCT: Incidence and interobserver agreement among radiologists and pneumologists. Eur J Radiol 2012; 81(12):4161-66 Studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.

Role of Lung Perfusion Scintigraphy in Relation to Chest Computed Tomography and Pulmonary Function in the Evaluation of Candidates for Lung Volume Reduction Surgery

Thurnheer R, Engel H, Weder W, et al. Role of Lung Perfusion Scintigraphy in Relation to Chest Computed Tomography and Pulmonary Function in the Evaluation of Candidates for Lung Volume Reduction Surgery. Am J Respir Crit Care Med 1999;159(1):301-10 Studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.

Long-term follow-up after bronchoscopic lung volume reduction in patients with emphysema

Venuta F, Anile M, Diso D, et al. Long- term follow-up after bronchoscopic lung volume reduction in patients with emphysema. Eur Respir J 2012;39:1084-1089

This study involved the Zephyr^® Endobronchial Valve. Zephyr is a registered trademark of PulmonX, Inc.

Atelectasis and survival after bronchoscopic lung volume reduction for COPD

Hopkinson NS, Kemp SV, Toma TP, et al. Atelectasis and survival after bronchoscopic lung volume reduction for COPD. Eur Respir J 2011;37:1346-1351

This study involved the Zephyr^® Endobronchial Valve. Zephyr is a registered trademark of PulmonX, Inc.

Multicentre European study for the treatment of advanced emphysema with bronchial valves

Ninane V, Geltner C, Bezzi M, et al. Multicentre European study for the treatment of advanced emphysema with bronchial valves. Eur Respir J 2012; 39:1319–1325 DOI: 10.1183/09031936.00019711 This study was conducted using a bilateral partial-occlusion treatment approach, and patients were not evaluated for high heterogeneity or complete fissures for collateral ventilation. Subsequent studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.