Clinical Literature Library

A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema

Sterman D, Mehta A, Wood D, et al. A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema. Respiration 2010; 70:222-33 This study was conducted using a bilateral partial-occlusion treatment approach, and patients were not evaluated for high heterogeneity or complete fissures for collateral ventilation. Subsequent studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.

Treatment of Heterogenous Emphysema Using the Spiration IBV Valves

Springmeyer S, Bollinger C, Waddell T, et al. Treatment of heterogenous emphysema using the Spiration IBV Valves. Thorac Surg Clin 2009; 19:247-253

This study was conducted using a bilateral partial-occlusion treatment approach, and patients were not evaluated for high heterogeneity or complete fissures for collateral ventilation. Subsequent studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.

Computed Tomography Assessment of Lung Volume Changes After Bronchial Valve Treatment

Coxson H, Fauerbach P, Storness-Bliss C, et al. Computed Tomography Assessment of Lung Volume Changes After Bronchial Valve Treatment. Eur Respir J 2008; 32:1443-50 This study was conducted using a bilateral partial-occlusion treatment approach, and patients were not evaluated for high heterogeneity or complete fissures for collateral ventilation. Subsequent studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.

A Multicenter Trial of an Interbronchial Valve for Treatment of Severe Emphysema

Wood D, McKenna R, Yusen R, et al. A Multicenter Trial of an Interbronchial Valve for Treatment of Severe Emphysema. J Thora Cardiovasc Surg 2007; 133:65-73 DOI:10.1016/j.jtcvs.2006.06.051 This study was conducted using a bilateral partial-occlusion treatment approach, and patients were not evaluated for high heterogeneity or complete fissures for collateral ventilation. Subsequent studies suggest that an optimal treatment approach may involve complete occlusion of the single most diseased lobe, and careful selection of appropriate patients with high heterogeneity and complete fissures.